It's in the historic city center of Como where only residents or taxi can enter.
So, if you are arriving By Car park your car outside the wall:
Parking facilities in the Como center:
By Train
By train in Como you get to the stations:
Train timetable: www.trenitalia.com
By Ferry
Imbarcadero di Como - Lungo Lario Trento, 1 - 400 m (5 min)
Navigation timetable: www.navigazionelaghi.it/ita/c_orari.asp